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Rheumatoid arthritis - adalimumab, etanercept and infliximab (TA130) |
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Adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis
This guidance recommends adalimumab, etanercept and infliximab as possible treatments for people with rheumatoid arthritis who:
- have already tried methotrexate and another disease-modifying anti-rheumatic drug (DMARD), and
- have 'active' rheumatoid arthritis, as assessed by a rheumatologist on two separate occasions. People who are treated with adalimumab, etanercept or infliximab should normally also be given methotrexate. If methotrexate does not suit them, they may be given adalimumab or etanercept on its own.
This guidance partially replaces TA36 'Guidance on the use of etanercept and infliximab for the treatment of rheumatoid arthritis' issued in March 2002. This review and re-appraisal has additionally included adalimumab for the treatment of rheumatoid arthritis, and has taken into account changes in the marketing authorisations for infliximab and etanercept.
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Other information
How this guidance was produced
Background information
This page was last updated: 07 October 2011
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Guidance formats
Rheumatoid arthritis - adalimumab, etanercept and infliximab
Guideline for patients and carers (PDF)
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Implementation tools and resources
- Audit support
- Clinical audit tool
- Costing template
- Biologic drugs for the treatment of inflammatory disease in rheumatology, dermatology and gastroenterology commissioning guide
See this guidance in practice
Patient
The summary of the key recommendations in the guidance written for patients, carers and those with little medical knowledge and may be used in local patient information leaflets.
Quick Reference Guide
The quick reference guide presents recommendations for health professionals
NICE Guidance
The published NICE clinical guidance, contains the recommendations for health professionals and NHS bodies.
Full Guidance
The published full clinical guidance for specialists with background, evidence, recommendations and methods used.

