Aflibercept in combination with irinotecan and fluorouracil-based therapy for treating metastatic colorectal cancer that has progressed following prior oxaliplatin-based chemotherapy

NICE technology appraisals [TA307] Published date:

Aflibercept taken with FOLFIRI (a chemotherapy combination made up of 3 drugs) is not recommended for metastatic colorectal cancer that has got worse after taking chemotherapy that includes oxaliplatin.

What does this mean for me?

Aflibercept should not normally be prescribed on the NHS for metastatic colorectal cancer. Your doctor should talk to you about other treatment options available to you.

If you are already taking aflibercept for colorectal cancer, you should be able to continue taking it until you and your healthcare professional decide it is the right time to stop.

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