Canagliflozin in combination therapy for treating type 2 diabetes

NICE technology appraisals [TA315] Published date:

If a person needs to take 2 antidiabetic drugs, canagliflozin is recommended as a possible treatment for people with type 2 diabetes when taken with a drug called metformin, only if the person:

  • cannot take a type of drug called a sulfonylurea or
  • is at significant risk of hypoglycaemia or its consequences.

If a person needs to take 3 antidiabetic drugs, canagliflozin is recommended as a possible treatment when taken with either metformin and a sulfonylurea, or metformin and a type of drug called a thiazolidinedione.

Canagliflozin is recommended as a possible treatment taken with insulin, with or without other antidiabetic drugs.

What does this mean for me?

If you have type 2 diabetes, and your doctor thinks that canagliflozin, as described above, is the right treatment, you should be able to have the treatment on the NHS.

Canagliflozin should be available on the NHS within 3 months of the guidance being issued.

If you are not eligible for treatment as described above, you should be able to continue taking canagliflozin until you and your doctor decide it is the right time to stop.

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