| TA99 |
Renal transplantation - immunosuppressive regimens for children and adolescents (TA99) |
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chronic kidney disease
Fast, easy summary view of NICE guidance on 'chronic kidney disease'
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Immunosuppressive therapy for renal transplantation in children and adolescents
NICE has made the following recommendations about the use of immunosuppressive drugs in children and adolescents receiving kidney transplants:
Basiliximab and daclizumab
Doctors should consider using basiliximab or daclizumab for induction therapy. These drugs should only be used with a combination of other drugs that includes ciclosporin.Tacrolimus
Tacrolimus is a calcineurin inhibitor and can be used instead of ciclosporin when a person needs a calcineurin inhibitor as part of their initial therapy or maintenance therapy.Mycophenolate mofetil
Doctors should consider using mycophenolate mofetil as part of immunosuppressive treatment after kidney transplantation only when a person has to stop taking a calcineurin inhibitor, or has to take a lower dose.Mycophenolate sodium
NICE does not recommend the use of mycophenolate sodium as part of immunosuppressive regimens for children or adolescents undergoing kidney transplantation.Sirolimus
NICE does not recommend the use of sirolimus as part of immunosuppressive regimens for children or adolescents undergoing kidney transplantation, except when a patient has had to stop taking calcineurin inhibitors because of their side effects.-
Other information
NICE Pathways
This guidance has been incorporated into the following NICE Pathways, along with other related guidance and products.
Visit the NICE Pathway: chronic kidney disease
How this guidance was produced
Background information
This page was last updated: 11 February 2011
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Guidance formats
- Web format
- Quick reference guide (PDF)
- Full Guidance (PDF)
- Patient version (PDF)
- TA99 Cyffuriau i atal trawsblaniadau aren mewn plant a phobl ifanc rhag cael eu gwrthod: deall canllawiau NICE
Renal transplantation - immunosuppressive regimens for children and adolescents
Guideline for patients and carers (PDF)
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Implementation tools and resources
See this guidance in practice
Patient
The summary of the key recommendations in the guidance written for patients, carers and those with little medical knowledge and may be used in local patient information leaflets.
Quick Reference Guide
The quick reference guide presents recommendations for health professionals
NICE Guidance
The published NICE clinical guidance, contains the recommendations for health professionals and NHS bodies.
Full Guidance
The published full clinical guidance for specialists with background, evidence, recommendations and methods used.
