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Colon cancer (adjuvant) - capecitabine and oxaliplatin

Capecitabine and oxaliplatin in the adjuvant treatment of stage III (Dukes' C) colon cancer

Guidance type:  Technology appraisal
Date issued:  April 2006

We will consult on our review plans for this guidance in June 2009.

Reference:  TA100

Summary

Capecitabine and oxaliplatin are recommended as possible adjuvant treatments after surgery for stage III (Dukes’ C) colon cancer, when used in the following ways:

  • capecitabine on its own
  • oxaliplatin together with 5-fluorouracil and folinic acid.

The choice of treatment should be decided jointly by the individual and their doctors, after they have discussed the options. This discussion should cover any contraindications to the treatments (reasons why a particular medicine might not be suitable for the person), the possible side effects of the treatments, and the different ways they can be given. It should also take into account the person’s clinical condition and individual preferences.

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