Metastatic malignant disease of unknown primary origin: Diagnosis and management of metastatic malignant disease of unknown primary origin

NICE guidelines [CG104] Published date:

Review decision date: TBC

Review decision: 

Following consultation with stakeholders this guideline has now been placed on the static list. 

The advice in the NICE guideline covers:

  • the treatment and care of adults with suspected or diagnosed cancer of unknown primary, including people who have been treated for cancer before.

In this guideline ‘cancer of unknown primary’ refers to a particular type of cancer, called carcinoma.

It does not specifically look at:

  • children (under 18) with cancer of unknown primary
  • adults with cancer, or likely to have cancer, that has spread (also called metastatic cancer) with a known site of primary origin
  • adults with cancer that is not carcinoma (for example lymphoma, melanoma, sarcoma).

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