This clinical guideline updates and replaces NICE technology appraisal 93 (published in August 2005). It offers evidence-based advice on the diagnosis and management of colorectal cancer.
In colorectal cancer, cells in the colon or in the rectum start to grow in an uncontrolled way, forming a lump called the primary cancer or primary tumour. Like other cancers, colorectal cancer starts in a small area but can spread to other parts of the body to form metastatic tumours.
The term colorectal cancer covers cancers in both the colon (colon cancer) and the rectum (rectal cancer).
Recommendations on surgery and colonic stents in acute large bowel obstruction and on stage I rectal cancer in sections 1.2.2 and 1.2.4 have been added. The addendum to NICE clinical guideline 131 contains details of the methods and evidence used to update these recommendations.