Review decision date: August 2014

Review decision: 

This guideline will shortly be checked to see if it needs updating, please register as a stakeholder to be informed about the decision.

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Next review date: September 2016

This guideline covers the diagnosis and management of venous thromboembolic diseases in adults (aged 18 and over), and the role of thrombophilia testing. It aims to clarify which diagnostic tests should be used, reduce variation in pharmacological therapies, and provide guidance on when thrombophilia testing is useful.

In November 2015 new recommendations were added on elastic graduated compression stockings, and on pharmacological therapy for patients with a pulmonary embolism who are haemodynamically stable.


This updated guideline includes recommendations on:

  • diagnosis
  • treatment
  • investigations for cancer
  • thrombophilia testing

Who is it for?

  • commissioners and providers of venous thromboembolism services.
  • healthcare professionals in primary, secondary and tertiary care.
  • adults (18 and over) with suspected or confirmed deep vein thrombosis or pulmonary embolism, and their families and carers.
  • first-degree relatives of people with inherited thrombophilia or other venous thromboembolic diseases
  • National Institute for Health and Care Excellence (NICE) accreditation logo