This guideline covers the diagnosis and management of venous thromboembolic diseases in adults (aged 18 and over), and the role of thrombophilia testing. It aims to clarify which diagnostic tests should be used, reduce variation in pharmacological therapies, and provide guidance on when thrombophilia testing is useful.

This guideline was previously called venous thromboembolic diseases: the management of venous thromboembolic diseases and the role of thrombophilia testing.

In November 2015 new recommendations were added on elastic graduated compression stockings, and on pharmacological therapy for patients with a pulmonary embolism who are haemodynamically stable.


This updated guideline includes recommendations on:

Who is it for?

  • Commissioners and providers of venous thromboembolism services
  • Healthcare professionals in primary, secondary and tertiary care
  • Adults (18 and over) with suspected or confirmed deep vein thrombosis or pulmonary embolism, and their families and carers
  • First-degree relatives of people with inherited thrombophilia or other venous thromboembolic diseases

Guideline development process

How we develop NICE guidelines 

Next review date: September 2016

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