Prophylaxis against infective endocarditis: Antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional procedures

NICE guidelines [CG64] Published date:

Review decision: 

Following the publication of new research at the AHA meeting in Chicago on 18 November 2014 showing an increase in the incidence of infective endocarditis in the UK, NICE has launched an immediate review of CG64 on Prophylaxis for Infective Endocarditis.

Read more about our decision.

 

Next review date: TBC

The advice in this NICE guideline covers:

Patients who are at risk of infective endocarditis, specifically:

  • adults and children with certain problems affecting the structure of the heart (such as a replacement heart valve or hypertrophic cardiomyopathy)
  • adults and children who have previously had infective endocarditis (whether or not they have an underlying cardiac problem)
  • people having any of these procedures:

- any dental procedure

- any obstetric or gynaecological procedure, or childbirth

- any procedure on the bladder or urine system

- any procedure on the gullet, stomach or intestines

- any procedure on the airways, including ear, nose and throat procedures and bronchoscopy (a test used to diagnose some lung problems).

It does not specifically look at:

  • people at risk of infective endocarditis who do not have heart problems (such as intravenous drug users)
  • people having procedures that aren't in the list above

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