The National Institute for Health and Clinical Excellence (NICE) issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on living donor liver transplantation in November 2006. In accordance with the Interventional Procedures Programme Process Guide, guidance on procedures with special arrangements are reviewed 3 years after publication and the procedure is reassessed if important new evidence is available.

The guidance was considered for reassessment in November 2009 and it was concluded that NICE will not be updating this guidance at this stage. However, if you believe there is new evidence which should warrant a review of our guidance, please contact us via the email address below.


Many diseases can damage the liver. If damage is severe, a liver transplantation may be necessary. Living-donor liver transplantation is the replacement of a diseased liver with part of a healthy liver from a donor (usually a relative or spouse).

Coding recommendations

For the donor:

X45.8 Other specified donation of organ

Z30.1 Liver

For the recipient:

J01.1 Orthotopic transplantation of liver NEC

Y99.2 Live related donor NEC or Y99.3 Live unrelated donor or Y99.5 Live matched related donor or Y99.6 Live unmatched related donor