The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on corneal endothelial transplantation.

  • Description

    Some diseases can effect the clear section at the front of the eye (the cornea), and in particular the layers that help maintain its clarity (the endothelium). This procedure aims to replace only the innermost layers of the cornea with a healthy section from a donor eye without disturbing the overall structure of the cornea. 

  • OPCS4.6 Code(s)

    C44.3 Endothelial graft to cornea

    Includes: Endothelial keratoplasty

    Y01.4   Alloreplacement of organ from cadaver heart beating NOC


    Y01.5   Alloreplacement of organ from cadaver heart non-beating NOC


    Y01.6 Alloreplacement of organ from cadaver NOC

    The NHS Classifications Service has advised NICE that currently these are the most suitable OPCS-4 codes to describe this procedure. The OPCS-4 classification is designed to categorise procedures for analysis and it is not always possible to identify a procedure uniquely.

    The NHS Classifications Service of NHS Connecting for Health is the central definitive source for clinical coding guidance and determines the coding standards associated with the classifications (OPCS-4 and ICD-10) to be used across the NHS.   The NHS Classifications Service and NICE work collaboratively to ensure the most appropriate classification codes are provided.

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