Cinacalcet for the treatment of secondary hyperparathyroidism in patients with end-stage renal disease on maintenance dialysis therapy

NICE technology appraisals [TA117] Published date:

Cinacalcet is not generally recommended for treating people on dialysis who have hyperparathyroidism because of their kidney disease. However, it is recommended for people on dialysis who:

  • have very high levels of parathyroid hormone in their blood that can't be lowered by other treatments, and
  • cannot have an operation to remove the parathyroid glands (a parathyroidectomy), because of the risks involved.

People who do receive cinacalcet should have regular checks. Treatment should be stopped if the parathyroid hormone levels in their blood do not fall substantially within 4 months.

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