6 Recommendations for further research
6.1 The Appraisal Committee considered that further research into the effectiveness of anti-VEGFs in wet AMD could include studies:
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about the cost effectiveness of ranibizumab compared with bevacizumab
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to investigate the long-term effects of anti-VEGFs in patients with AMD, including effects on visual acuity, anatomical damage to the macula, quality of life and adverse events
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to establish the appropriate duration and optimal treatment regimen in terms of frequency of injections.