SonoVue (sulphur hexafluoride microbubbles) – contrast agent for contrast-enhanced ultrasound imaging of the liver

NICE diagnostics guidance [DG5] Published date:

NICE has assessed SonoVue to help the NHS decide whether to use this product.

SonoVue is a substance that is injected into the bloodstream to help make ultrasound pictures clearer. NICE looked at SonoVue when it is used with ultrasound to look at the liver. It can give doctors more information about abnormal-looking areas in the liver than normal ultrasound, which can help with the diagnosis.

NICE has said that SonoVue is recommended for use with ultrasound for examining abnormal-looking areas in the liver that are noticed, but cannot be properly identified, using normal ultrasound. These areas may have been noticed during routine scanning. If they were noticed when looking for cancer that has spread from another part of the body, SonoVue is recommended if the person cannot have or does not want a CT (computed tomography) scan. If they were noticed in someone with cirrhosis who is having their liver checked, SonoVue is recommended if the person cannot have or does not want an MRI (magnetic resonance imaging) scan.

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