Guidance
3 Committee considerations
The evidence
3.1 To inform the committee, NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 6 sources, which was discussed by the committee. The evidence included 4 systematic reviews, 1 randomised controlled trial and 1 cohort study and is presented in table 2 of the interventional procedures overview. Other relevant literature is in the appendix of the overview.
3.2 The specialist advisers and the committee considered the key efficacy outcomes to be: fracture healing or union, functional outcomes and quality of life.
3.3 The specialist advisers and the committee considered the key safety outcome to be: need for subsequent reoperation.
3.4 Three commentaries from patients who had experience of this procedure were received, which were discussed by the committee.