Resource impact statement

No significant resource impact is anticipated

NICE has recommended relugolix–estradiol–norethisterone acetate as an option for treating moderate to severe symptoms of uterine fibroids in adults of reproductive age.

Relugolix–estradiol–norethisterone acetate offers a new option for patients in an area of high unmet need. Relugolix–estradiol–norethisterone acetate is an oral pharmacological treatment that can be used on a long-term basis for the treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age. The comparator treatment, injectable gonadotrophin-releasing hormone agonists requires clinic visits.

We do not expect this guidance to have a significant impact on resources; that is, the resource impact of implementing the recommendations in England will be less than £5 million per year (or approximately £9,000 per 100,000 population, based on a population for England of 56.3 million people).

This is because the technology is a further treatment option and is available at a similar price to the current treatment options. Since the technology is taken orally and does not require clinic visits there is expected to be a capacity benefit as a result. However, this is not expected to be significant at a national level.

This technology is commissioned by integrated care systems. Providers are NHS hospital trusts and primary care providers.

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