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Individual research recommendation details

Recommendation details

Recommendation ID: CG102/1
Question: Symptoms and signs of bacterial meningitis and meningococcal disease:- What are the symptoms and signs of bacterial meningitis and meningococcal disease in children and young people aged under 16 years that differentiate between these conditions and minor self-limiting infections (including those characterised by fever)?
Page: 36
Any explanatory
notes (if applicable):
Why this is important:- Research is needed from primary and secondary care settings on the diagnostic accuracy of symptoms and signs suggestive of bacterial meningitis and meningococcal disease in children and young people. The research should focus on identifying individual symptoms and signs, or groups of symptoms and signs that are effective as predictors of bacterial meningitis and meningococcal disease. These symptoms and signs should also differentiate effectively between these conditions and minor self-limiting infections. The research should include consideration of the effectiveness of symptoms and signs of acute feverish illness as predictors of meningococcal disease. Consideration should also be given to the age of the child or young person (in terms of the relevance of particular symptoms and signs) and the clinical setting at presentation. Suitable study designs would include diagnostic accuracy studies as well as observational studies (such as caseā??control studies), and the research could include a systematic review of studies that have already been published.

Source guidance details

Comes from guidance: Bacterial meningitis and meningococcal septicaemia
Number: CG102
Date issued: Jun 2010

Research needed into:

Effectiveness of treatment: No
Cost of treatment: No
Implementation of treatment: No
Quality of life: No
Methods of research: No

Other details

Is this a recommendation for the use of a technology only in the context of research?: No
Is it a recommendation that suggests collection of data or the establishment of a register?: No
Recommendation priority: Unrated
Recommendation status: Research Pending
Notes: 0
Date this record updated: 13-09-2010

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Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.