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Individual research recommendation details

Recommendation details

Recommendation ID: CG102/2
Question: Predictive value of blood test results and cerebrospinal fluid (CF) findings:- What are the normal ranges for blood and CSF parameters in children and young people in the UK?
Page: 36
Any explanatory
notes (if applicable):
Why this is important:- Bacterial meningitis is a rare disease that is not easily distinguishable clinically from aseptic meningitis. It is, however, important to recognise those children who are most likely to have bacterial meningitis to direct appropriate management of the condition and to avoid inappropriate treatment of aseptic meningitis. Since the introduction of vaccines to protect against Hib, meningococcus serogroup C and pneumococcus, no high quality studies involving previously healthy children and young people have been conducted in the UK to determine normal ranges for blood test results or cerebrospinal fluid (CSF) findings in bacterial and aseptic meningitis. Such studies are needed to provide reference values to help interpret blood test results and CSF findings in children (especially neonates) and young people with suspected bacterial meningitis.

Source guidance details

Comes from guidance: Bacterial meningitis and meningococcal septicaemia
Number: CG102
Date issued: Jun 2010

Research needed into:

Effectiveness of treatment: No
Cost of treatment: No
Implementation of treatment: No
Quality of life: No
Methods of research: No

Other details

Is this a recommendation for the use of a technology only in the context of research?: No
Is it a recommendation that suggests collection of data or the establishment of a register?: No
Recommendation priority: Unrated
Recommendation status: Research Pending
Notes: 0
Date this record updated: 13-09-2010

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Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.