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Individual research recommendation details

Recommendation details

Recommendation ID: CG127/5
Question: Step 4 antihypertensive treatment:- In adults with hypertension, which drug treatment (diuretic therapy versus other step 4 treatments) is the most clinically and cost effective for step 4 antihypertensive treatment?
Page: 25
Any explanatory
notes (if applicable):
Why this is important: - Although this guideline provides recommendations on the use of further diuretic therapy for treatment at step 4 (resistant hypertension), they are largely based on post-hoc observational data from clinical trials. More data are needed to compare further diuretic therapies, for example a potassiumsparing diuretic with a higher-dose thiazide-like diuretic, and to compare diuretic therapy with alternative treatment options at step 4 to define whether further diuretic therapy is the best option.

Source guidance details

Comes from guidance: Hypertension
Number: CG127
Date issued: Aug 2011

Research needed into:

Effectiveness of treatment: No
Cost of treatment: No
Implementation of treatment: No
Quality of life: No
Methods of research: No

Other details

Is this a recommendation for the use of a technology only in the context of research?: No
Is it a recommendation that suggests collection of data or the establishment of a register?: No
Recommendation priority: Unrated
Recommendation status: Research Pending
Notes: 0
Date this record updated: 30-08-2011

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This page was last updated: 20 March 2014

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Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.