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Individual research recommendation details

Recommendation details

Recommendation ID: CG57/3
Question: Early intervention:- What effect does improving the control of atopic eczema in the first year of life have on the long-term control and severity of atopic eczema and the subsequent development and severity of food allergy, asthma and allergic rhinitis?
Page: 33
Any explanatory
notes (if applicable):
Why this is important:- Uncontrolled atopic eczema in children may progress to chronic disease involving the production of auto-immune antibodies to the skin. Early intervention to restore the defective skin barrier might alter the course of atopic eczema by preventing allergen penetration. A systematic review is needed to evaluate the available evidence on these factors. The results should feed in to the design of a large randomised controlled trial investigating the long-term effect of controlling atopic eczema in the first year of life. Early effective treatment to control atopic eczema and the development of other atopic conditions would be extremely cost effective, have a major impact on service provision and improve the quality of life of children with atopic eczema and their parents and carers.

Source guidance details

Comes from guidance: Atopic eczema in children
Number: CG57
Date issued: Dec 2007

Research needed into:

Effectiveness of treatment: Yes
Cost of treatment: No
Implementation of treatment: No
Quality of life: No
Methods of research: No

Other details

Is this a recommendation for the use of a technology only in the context of research?: No
Is it a recommendation that suggests collection of data or the establishment of a register?: No
Recommendation priority: Unrated
Recommendation status: Research Pending
Notes: Headings integrated
Date this record updated: 11-03-2008

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Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.