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Individual research recommendation details

Recommendation details

Recommendation ID: CG61/5
Question: Herbal medicines:- Are Chinese and non-Chinese herbal medicines safe and effective as first-line therapy in the treatment of [Irritable bowel syndrome] (IBS), and which is the most effective and safe option?
Page: 20
Any explanatory
notes (if applicable):
Why this is important:- Reviews of herbal medicines suggest a positive effect on the control of IBS symptoms, but evidence is limited and not sufficient to make recommendations (eight comparisons from the six trials provide heterogeneous data, which are very difficult to interpret). A large randomised placebo-controlled trial is proposed, comparing Chinese and non-Chinese herbal medicines (both single and multiple compounds) that are available in the UK as standard preparations. Participants should be adults with a positive diagnosis of IBS, and they should be stratified by type of IBS and then randomised to treatments. The primary outcome should be global improvement in IBS symptoms, with symptom scores recorded using a validated scale. Health-related quality of life should also be measured, and adverse events recorded. Study outcomes should be assessed 12, 26 and 52 weeks post intervention.

Source guidance details

Comes from guidance: Irritable bowel syndrome
Number: CG61
Date issued: Feb 2008

Research needed into:

Effectiveness of treatment: Yes
Cost of treatment: No
Implementation of treatment: No
Quality of life: Yes
Methods of research: No

Other details

Is this a recommendation for the use of a technology only in the context of research?: No
Is it a recommendation that suggests collection of data or the establishment of a register?: No
Recommendation priority: Unrated
Recommendation status: Research Pending
Notes: paras separated, headings integrated. [Irritable bowel syndrome] inserted
Date this record updated: 05-06-2008

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Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.