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Summary of Results

Health Topic:   Mental health and behavioural conditions
Guidance:   Smoking cessation - varenicline
Description:   The summary of the published technology appraisal on Smoking cessation - varenicline . It links to the published guidance and key documents.

NICE implementation uptake reports

Implementation uptake report Assessment Published Date Coverage

External literature

External literature Assessment Coverage

NHS Information Centre for Health and Social Care (2009) Use of NICE appraised medicines in the NHS in England-Experimental Statistics

Description: Estimated numbers of eligible patients were derived from NICE costing templates. Data for varenicline were obtained from Prescription and Cost system (ePACT). The NICE costing template expected an annual number of 62.4 thousand patients in 2008. The BNF recommends a 12 week treatment course. This gives a predicted use of 5,245.2 thousand doses per year. The observed use in 2008 was 12,028.5 thousand defined daily doses, a ratio of 2.3 to 1.

Practice appears not to be in line with guidance National

The NHS Information Centre for Health and Social Care (2011) Use of NICE-appraised medicines in the NHS in England-2009, Experimental Statistics

Description: This is the second report commissioned by the Metrics Working Group to look at the variation in use of postively appraised medicines in relation to the expected use as predicted by NICE. In all, 47 medicines in 18 groups, relating to 29 technology appraisals were considered. Out of the 12 groups where a comparison could be made (these are presented in Section 1 of the technology section results), observed use by the NHS in England was higher than the predicted use for eight and lower for three.

Not graded National

Health and Social Care Information Centre (2012) Use of NICE-appraised medicines in the NHS in England - 2010 and 2011, Experimental Statistics

Description: This is the 3rd report published by the HSCIC on behalf of the DH to look at the variation in use of positively appraised medicines in relation to the expected use as predicted by NICE. In all, 52 medicines in 25 groups, relating to 35 technology appraisals were considered. Out of the 12 groups where a comparison could be made, observed use by the NHS in England was higher than the predicted use for 6 and lower for 6. For one drug group use was lower on one measure, and higher on another.

Not graded National

Health and Social Care information Centre (2012) NHS Stop Smoking Services: England, April 2012 to June 2012 (Q1 - Quarterly report)

Description: This quarterly report presents provisional results from the monitoring of the NHS Stop Smoking Services in England during 1 April 2012 to 30 June 2012. Analyses of pharmacotherapy received showed 64% of the 176,945 people setting a quit date received Nicotine Replacement Therapy (NRT) only. A further 26% received varenicline only, 1% bupropion only, 2% both NRT and varenicline and <1% both NRT and bupropion. 4% did not receive any pharmacotherapy and treatment type was unknown for 3%.

Doubts about or mixed impact in practice National

Health and Social Care Information Centre (2013) NHS Stop Smoking Services: England, April 2012 to September 2012 (Q2 - Quarterly report)

Description: This quarterly report presents provisional results from the monitoring of the NHS Stop Smoking Services in England during 1 April 2012 to 30 September 2012. Analyses of pharmacotherapy received showed 64% of the 341,379 people setting a quit date received Nicotine Replacement Therapy (NRT) only. A further 26% received varenicline only, 1% bupropion only, 2% both NRT and varenicline and <1% both NRT and bupropion. 5% did not receive any pharmacotherapy and treatment type was unknown for 3%.

Doubts about or mixed impact in practice National

Health and Social Care Information Centre (2013) NHS Stop Smoking Services: England, April 2012 to December 2012 (Q3 - Quarterly report)

Description: This quarterly report presents provisional results from the monitoring of the NHS Stop Smoking Services in England during 1 April 2012 to 31 December 2012. Analyses of pharmacotherapy received showed 64% of the 502,917 people setting a quit date received Nicotine Replacement Therapy (NRT) only. A further 26% received varenicline only, 1% bupropion only, 2% both NRT and varenicline and <1% both NRT and bupropion. 5% did not receive any pharmacotherapy and treatment type was unknown for 3%.

Doubts about or mixed impact in practice National

Health and Social Care Information Centre (2013) Statistics on Smoking: England, 2012

Description: This report presents information on smoking including prevalence, habits, attitudes, NHS costs and the effect on health drawn together from a variety of sources. It presents data on the number of prescription items used to help people in England stop smoking. In 2011/12, there were just over 2.5 million prescription items to help people stop smoking (down from 2.6 million in 2010/11). Of these, 1.5 million were for Nicotine Replacement Therapy, 957,000 for Varenicline and 30,000 for Bupropion.

Doubts about or mixed impact in practice National

Health and Social Care Information Centre (2013) Statistics on Smoking: England, 2013

Description: This report presents information on smoking including prevalence, habits, attitudes, NHS costs and the effect on health drawn together from a variety of sources. It presents data on the number of prescription items used to help people in England stop smoking. In 2012/13, there were just over 2.2 million prescription items to help people stop smoking (down from 2.5 million in 2011/12). Of these, 1.3 million were for Nicotine Replacement Therapy, 859,000 for Varenicline and 26,000 for Bupropion.

Doubts about or mixed impact in practice National

Health and Social Care Information Centre (2013) NHS Stop Smoking Services England: April 2013 to June 2013 (Q1 - Quarterly report)

Description: This quarterly report presents provisional results from the monitoring of the NHS Stop Smoking Services in England during 1 April 2013 to 30 June 2013. Analyses of pharmacotherapy received showed 64% of the 138,106 people setting a quit date received Nicotine Replacement Therapy (NRT) only. A further 26% received varenicline only, 1% bupropion only, 2% both NRT and varenicline and <1% both NRT and bupropion. 5% did not receive any pharmacotherapy and treatment type was unknown for 3%.

Doubts about or mixed impact in practice National

Harrison, R. et al (2012) Smoking Prevalence and Smoking Cessation Amongst Acute Medical Admissions Thorax 2012;67:A153-A154

Description: The purpose of this study was to identify smoking prevalence at the time of hospital admission and to evaluate provision of smoking cessation advice and nicotine replacement therapy (NRT) prescription. Data were collected on 185 patients at University Hospital Southampton NHS Foundation Trust. Of these 85% had their smoking status clearly documented. Only 30% of smokers were provided with cessation advice. 69.5% of smokers did not have NRT prescribed, but only 19.5% did not wish to receive NRT.

Doubts about or mixed impact in practice Local

Health and Social Care Information Centre (2014) NHS Stop Smoking Services England: April 2013 to September 2013 (Q2 - Quarterly report)

Description: This quarterly report presents provisional results from the monitoring of the NHS Stop Smoking Services in England during 1 April 2013 to 30 September 2013. Analyses of pharmacotherapy received showed 64% of the 268,644 people setting a quit date received Nicotine Replacement Therapy (NRT) only. A further 26% received varenicline only, 1% bupropion only, 2% both NRT and varenicline and <1% both NRT and bupropion. 5% did not receive any pharmacotherapy and treatment type was unknown for 3%.

Doubts about or mixed impact in practice National

Health and Social Care Information Centre (2013) Statistics on NHS Stop Smoking Services, England - April 2012 to March 2013

Description: This report presents results from the monitoring of NHS Stop Smoking Services in England during 2012/13 and supersedes results for Q1-3 previously published. Analysis of pharmacotherapy received showed 65% of the 667,203 people setting a quit data received Nicotine Replacement Therapy (NRT) only. A further 25% received Varenicline only, 1% Bupropion only, 2% both NRT and Varenicline and <0.1% both NRT and Bupropion. 5% did not receive any pharmacotherapy and treatment type was unknown for 3%.

Doubts about or mixed impact in practice National

This page was last updated: 01 January 2014

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Selected, reliable information for health and social care in one place

Accessibility | Cymraeg | Freedom of information | Vision Impaired | Contact Us | Glossary | Data protection | Copyright | Disclaimer | Terms and conditions

Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.