Recommendations for research

1 Most effective way of identifying risk of critical illness

What is the most effective way of identifying patients at risk of critical illness-associated physical morbidity, psychological morbidity and cognitive dysfunction and how can the disease progress and response to interventions be monitored?

2 Therapeutic strategies

In patients at high risk, which therapeutic strategies are the most clinically and cost effective at reducing the prevalence and severity of critical illness-associated physical morbidity, psychological morbidity and cognitive dysfunction?

3 Specific therapeutic strategies

In patients with established morbidity, which specific therapeutic strategies are the most clinically and cost effective at reducing the magnitude of critical illness-associated physical morbidity, psychological morbidity and cognitive dysfunction?

4 Organised critical care rehabilitation for patients at high risk

For patients at high risk of critical illness-associated morbidity, what is the clinical effectiveness and cost effectiveness of organised critical care rehabilitation versus usual care on physical and psychological functioning, participation and quality of life?

5 Organised critical care rehabilitation for patients not at high risk

For those patients not identified as at high risk of critical illness-associated morbidity, what is the clinical effectiveness and cost effectiveness of organised critical care rehabilitation versus usual care on physical, psychological functioning, participation and quality of life?

  • National Institute for Health and Care Excellence (NICE)