Commissioning through Evaluation (CtE) programme

This formal evaluation programme collects new clinical and patient experience data. It gives a limited number of patients access to treatments that:

  • show significant promise for the future
  • aren't currently funded by the NHS.

This ensures that each CtE scheme provides valuable new data to inform future commissioning policy decisions.

Programme phases

Phase 1 - recruitment

Each CtE scheme recruits an agreed number of patients. A few selected centres across England run the schemes. We help to identify the total number of patients needed to support data analysis. Schemes will close when enough patients have been recruited to complete data analysis.

Phase 2 - analysis

The length of this phase depends on the evaluation measures agreed by clinicians and patients at the start of each scheme. A treatment, such as a novel cancer treatment, could need to be evaluated at 3 and 6 months to see if it has halted the disease process, or improved survival.

We advise NHS England on the follow up measures, including:

  • What the need is.
  • Their length.
  • How many patients need assessing, at the various points of follow-up, to complete the analysis.

Interventional procedure registers

Cardiff Cardiac Ablation PROM (C-CAP)

This is for patients undergoing cardiac ablation to threat an arrhythmia. It's made up of 2 questionnaires. The first is completed by patients before receiving a cardiac ablation procedure. The second is completed after the procedure.

C-CAP aims to identify changes in arrhythmia related symptoms and quality of life. The questionnaires also explore patient's expectations and experiences of their ablation procedure.

Airway Intervention Registry

Recurrent Respiratory Papillomatosis (RRP) causes wart-life growths in the airway. This can make it difficult to breathe, speak and carry out normal everyday activities. It's a rare condition that's more common and aggressive in children than adults, it affects 4 in every 100,000 children. There's no known cure for RRP. Symptoms are checked through regular hospital visits. Multiple therapies and procedure are needed to remove or shrink the growths which can grow back quickly. 

The Airway Intervention Registry aims to identify which RRP treatments currently used in NHS hospitals are the most effective and safest in the short and long term. It will also identify which patients report best to specific treatments, and those who are at higher risk of experiencing complications after treatment.