- Recommendation ID
- CG156/5
- Question
- Long-term effects of IVF with or without intracytoplasmic sperm injection in children:- What are the long-term (over 20 years) effects of IVF with or without intracytoplasmic sperm injection (ICSI) in children in the UK?
- Any explanatory notes
(if applicable) - Why this is important:- This topic is important in informing patients, service providers and society at large about the potential long-term safety of assisted reproduction. Both IVF and intracytoplasmic sperm injection (ICSI) involve manipulation of egg and sperm in the laboratory, with impacts on the development of the subsequent embryo. However, while the first successful live birth following IVF was over 30 years ago, there is relatively little long-term research on the subject. In the review undertaken in this guideline update, the longest length of follow-up in the studies reviewed was 20 years, and the larger studies had shorter follow-up periods.
Source guidance details
- Comes from guidance
- Fertility problems: assessment and treatment
- Number
- CG156
- Date issued
- February 2013
Other details
| Is this a recommendation for the use of a technology only in the context of research? | No |
| Is it a recommendation that suggests collection of data or the establishment of a register? | No |
| Last Reviewed | 27/02/2013 |