Recommendation ID
CG125/2
Question
Effectiveness of modality:- What factors determine the effectiveness of any modality of dialysis, including peritoneal dialysis?
Any explanatory notes
(if applicable)
Why this is important:- There are substantial barriers to using randomised controlled trials (RCTs) in research on dialysis modality. This is a particular challenge for dialysis in children because any UK study is unlikely to be adequately powered. Also, patient preference is such an important factor in the choice of modality that when RCTs have been set up recruitment targets have not been met, so results were uncertain and of limited value.
Qualitative evidence shows that that patients and healthcare professionals perceive many factors as influencing the effectiveness of dialysis. These include age (specifically age 65 years and older), level of support and family functioning (relationships, organisation, coping strategies and life events). However, there is little robust qualitative evidence in this area.
Further research is needed to identify factors that predict treatment success or failure. Outcomes should include clinical outcomes (including preservation of renal function and rates of infection), dropout rates, psychosocial factors, quality of life, and adherence.

Source guidance details

Comes from guidance
Chronic kidney disease (stage 5): peritoneal dialysis
Number
CG125
Date issued
July 2011

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No