Recommendation ID
CG129/6
Question
Timing of birth:- What is the incidence of perinatal and neonatal morbidity and mortality in babies born by elective birth in twin and triplet pregnancies?
Any explanatory notes
(if applicable)
Why this is important:- The existing evidence in relation to perinatal and neonatal outcomes associated with elective birth in twin and triplet pregnancies is limited in quantity and quality. Evidence suggests a consistently higher fetal death rate (at all gestational ages) in monochorionic twin pregnancies than in dichorionic twin pregnancies. It is uncertain whether elective birth in monochorionic twin pregnancies at 1 week earlier than recommended in the guideline (that is, from 35 weeks 0 days) would reduce fetal death rates significantly without increasing adverse neonatal outcomes significantly (for example, immaturity of the babies’ respiratory systems). The research could be conducted through national audits of perinatal and neonatal morbidities in babies born by elective birth in twin and triplet pregnancies, taking account of the chorionicity of the pregnancy and gestational age at birth. If data from more than one study were available, then the technique of meta-regression might be useful for determining the optimal timing of birth precisely (according to gestational age).

Source guidance details

Comes from guidance
Multiple pregnancy: antenatal care for twin and triplet pregnancies
Number
CG129
Date issued
September 2011

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No