Recommendation ID
CG130/1
Question
Optimal management of hyperglycaemia in acute coronary syndromes (ACS): What is the optimal management of hyperglycaemia in people with acute coronary syndrome who have diagnosed or previously undiagnosed diabetes?
Any explanatory notes
(if applicable)
Why this is important:- Existing studies on the optimal management of hyperglycaemia in people who have acute coronary syndromes (ACS) and diagnosed or previously undiagnosed diabetes are generally of poor quality.
It is recommended that a large randomised controlled trial is conducted for people with ACS and hyperglycaemia (blood glucose 11 mmol/litre and over) stratified by NSTEMI and STEMI and by known diabetes and without a previous diagnosis of diabetes.
The interventions for the trial should be intravenous insulin or subcutaneous insulin administered within 4 hours of presentation to hospital. The aim is to achieve blood glucose between 6 and 11 mmol/litre for at least 24 hours. The comparator should be standard care.

Source guidance details

Comes from guidance
Hyperglycaemia in acute coronary syndromes: management
Number
CG130
Date issued
October 2011

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No