- Recommendation ID
- Symptoms and signs of serious illness: - NICE recommends a UK-based epidemiological study on the symptoms and signs of serious illness. [new 2013]
- Any explanatory notes
- Why this is important:- The current recommendations on symptoms and signs in the NICE guideline are based on a series of heterogeneous studies (using different methods, populations, outcomes and of varying quality) and a degree of subjectivity was needed to bring these together in the guideline. Therefore, the NICE recommends that a large prospective UK-wide study (n=20,000 plus) should be undertaken comparing all of these symptoms and signs covered in the guideline. This would allow for a standardised comparison of each symptom and sign, and for validation of the existing 'traffic light' table.
The study should use a standardised data collection protocol. Where possible the study should link with routinely collected data sets, such as Hospital Episode Statistics. The study should include a variety of settings and locations – that is, wherever children present, including primary care. The primary outcome of the study should be the final diagnosis and results of treatment.
Source guidance details
- Comes from guidance
- Fever in under 5s: assessment and initial management
- Date issued
- May 2013
|Is this a recommendation for the use of a technology only in the context of research?||No|
|Is it a recommendation that suggests collection of data or the establishment of a register?||No|