Recommendation ID
Antipyretics:- NICE recommends that studies are conducted in primary care and secondary care to
determine whether examination or re-examination after a dose of antipyretic medication is of
benefit in differentiating children with serious illness from those with other conditions. [2007]
Any explanatory notes
(if applicable)
Why this is important:- Antipyretic medications are widely used in primary and secondary settings by parents and healthcare professionals. Children may therefore present to healthcare facilities having had a dose of antipyretics. Furthermore, the child's response to antipyretic drugs may be used as an indication of severity of illness, the rationale being that those with milder illness will either show greater improvement in condition or a greater reduction in their fever than children with more serious illnesses. However, it is not clear if such changes in condition are a valid and reliable method of differentiating children with serious illness from those with less serious conditions.

Source guidance details

Comes from guidance
Fever in under 5s: assessment and initial management
Date issued
May 2013

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No  
Last Reviewed 13/06/2013