Recommendation ID
CG166/4
Question
Maintenance treatment for people with mild to moderate ulcerative colitis:- What is the clinical and cost effectiveness of regular maintenance treatment compared with no regular treatment (but rapid standard treatment if a relapse occurs) in specific populations with mild to moderate ulcerative colitis?
Any explanatory notes
(if applicable)
Why this is important:- Maintenance treatment reduces the chance of relapses occurring, but for much of the time a drug is being taken with no obvious benefit, and it may have side effects. An exacerbation of ulcerative colitis can usually be effectively treated or stopped if treatment is given when the first symptoms or signs of a relapse appear. It may be both clinically and cost effective to manage ulcerative colitis in this way, with people receiving episodic treatment rather than taking a drug continuously. This form of treatment may be appropriate if relatively few (for example, 1 or 2) mild relapses occur per year. The study population would be people in whom mild to moderate ulcerative colitis of any extent is in remission and who are not taking immunomodulator or biological drugs.

Source guidance details

Comes from guidance
Ulcerative colitis: management
Number
CG166
Date issued
June 2013

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No  
Last Reviewed 15/07/2013