Recommendation ID
CG185/1
Question
Psychological interventions for young people with bipolar depression:- What is the clinical and cost effectiveness of structured psychological interventions for young people with bipolar depression?
Any explanatory notes
(if applicable)
There has been very little research regarding the clinical effectiveness of structured individual and group psychological interventions for children and young people with bipolar disorder. Research on unipolar depression in children and young people supports the effectiveness of cognitive behavioural therapy (CBT), interpersonal therapy (IPT) and short-term family therapy. However, there have been no published trials investigating clinical and functional outcomes for young people with bipolar depression. Given the increasing emphasis on early interventions in related conditions such as psychosis and unipolar depression, it is important to know the form of psychological therapy that can benefit young people with bipolar disorder. A high-quality, non-inferiority randomised controlled trial (RCT) should recruit young people during an acute episode of bipolar depression who are treated with structured psychological interventions (CBT compared with IPT). Interventions should be offered over 6–9 months, with a 9-month follow-up period. Key outcomes should include clinical recovery, symptom change, personal recovery or functional outcomes at the end of treatment and at 9-month follow-up, and cost effectiveness.

Source guidance details

Comes from guidance
Bipolar disorder: assessment and management
Number
CG185
Date issued
September 2014

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No  
Last Reviewed 15/10/2014