Recommendation ID
IPG456/1
Question
NICE encourages further research into sutureless aortic valve replacement for aortic stenosis. Studies should document patient selection, aortic cross-clamp times, cardiopulmonary bypass times, perioperative morbidity and specifically the incidence of paravalvular (and central) leaks in the short and long term. Research comparing outcomes of the procedure against those of standard surgical aortic valve replacement would be useful.
Any explanatory notes
(if applicable)
There is evidence of limited quality supporting the efficacy of sutureless aortic valve replacement for aortic stenosis in the short term. The evidence on safety raises no major concerns in the short term apart from the risk of paravalvular leak. There is concern about the risks of paravalvular and central leaks in the longer term. Most of the evidence on sutureless aortic valve replacement for aortic stenosis is from patients who would be at high risk from standard surgical aortic valve replacement and there is negligible comparative evidence versus standard surgery.
For patients with aortic stenosis for whom surgical aortic valve replacement is considered suitable and for whom it would not pose a high risk, sutureless aortic valve replacement for aortic stenosis should only be used in the context of research.

Source guidance details

Comes from guidance
Sutureless aortic valve replacement for aortic stenosis
Number
IPG456
Date issued
July 2013

Other details

Is this a recommendation for the use of a technology only in the context of research? Yes  
Is it a recommendation that suggests collection of data or the establishment of a register?   No  
Last Reviewed 31/07/2013