- Recommendation ID
- Is primary radical cystectomy more effective than primary intravesical BCG (Bacille Calmette-Guérin) in high risk non-muscle-invasive bladder cancer, in terms of quality of life and cancer-specific outcomes?
- Any explanatory notes
- Options for people with high-risk non-muscle-invasive bladder cancer include cystoscopy surveillance, BCG immunotherapy or radical surgery. To date, these have not been directly compared across the same population to understand their relative benefits. Bladder-sparing approaches avoid major surgery, but have a greater risk of cancer progression. The potential advantage of bladder-sparing approaches compared with cystectomy in maintaining quality of life may be offset by continuing concern about cancer progression and morbidity from treatment. Primary cystectomy may improve survival; however, it has high short-term risks and life-changing consequences. It will be overtreatment for those people whose cancer would not have progressed.
Source guidance details
- Comes from guidance
- Bladder cancer: diagnosis and management
- Date issued
- February 2015
|Is this a recommendation for the use of a technology only in the context of research?||No|
|Is it a recommendation that suggests collection of data or the establishment of a register?||No|