Recommendation ID
How can fetuses at risk of intrauterine death be identified in women with diabetes?
Any explanatory notes
(if applicable)
Unexpected intrauterine death remains a significant contributor to perinatal mortality in pregnant
women with diabetes. Conventional tests of fetal wellbeing (umbilical artery Doppler ultrasound,
cardiotocography and other biophysical tests) have been shown to have poor sensitivity for
predicting such events. Alternative approaches that include measurements of erythropoietin in the
amniotic fluid and MRI spectroscopy may be effective, but there is currently insufficient clinical
evidence to evaluate them. Well-designed randomised controlled trials that are sufficiently
powered are needed to determine whether these approaches are clinically and cost effective.

Source guidance details

Comes from guidance
Diabetes in pregnancy: management from preconception to the postnatal period
Date issued
February 2015

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No  
Last Reviewed 23/04/2015