Recommendation ID
NG83/1
Question

Radical treatment of squamous cell carcinoma of the oesophagus:- Does the addition of surgery to chemoradiotherapy improve disease-free and overall survival in
people with squamous cell carcinoma of the oesophagus?

Any explanatory notes
(if applicable)

Why this is important:- The aetiology of squamous cell carcinoma (SCC) of the oesophagus is changing. Patients with SCC are now fitter, with fewer co-morbidities than in previous years. Standard radical treatment for SCC of the oesophagus is usually chemo-radiotherapy, which is associated with a median survival of between 12 and 18 months. Given a fitter patient population, surgery may be a therapeutic option but its effectiveness in addition to chemoradiotherapy is unknown and a randomised controlled study to investigate whether the combination improves disease-free and overall survival would provide useful information to guide future clinical practice.


Source guidance details

Comes from guidance
Oesophago-gastric cancer: assessment and management in adults
Number
NG83
Date issued
January 2018

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No  
Last Reviewed 31/01/2018