The acquisition cost of ceftazidime/avibactam is higher than other intravenous antimicrobials that are commonly used for complicated intra‑abdominal infections, complicated urinary tract infections and hospital acquired pneumonia. A vial of ceftazidime/avibactam 2 g/0.5 g costs £85.70 excluding VAT (British National Formulary [BNF], October 2017).
Ceftazidime/avibactam is an intravenous antimicrobial that was studied mainly in hospitalised people. In practice, ceftazidime/avibactam will be prescribed and administered within a hospital setting. Ceftazidime/avibactam is not included on the high cost drug exclusions list and so from a commissioning perspective the tariff for the inpatient episode will remain the same whichever antimicrobial is used for the indications discussed in this evidence summary.