The content of this evidence summary was up-to-date on 18 June 2020. See summaries of product characteristics (SPCs), British national formulary (BNF) or the MHRA, NHS or NICE websites for up-to-date information.
Vitamin D is important for bone and muscle health. It has also been hypothesised that vitamin D may have a role in the body's immune response to respiratory viruses. Although sunlight exposure is the major source of vitamin D for most people, it can also be obtained from the diet or supplements. The 2 major forms of vitamin D, vitamin D3 (colecalciferol) and vitamin D2 (ergocalciferol), are licensed for the prevention and treatment of vitamin D deficiency. Vitamin D supplements are not specifically licensed for preventing or treating any infection, including the novel coronavirus infection that causes COVID‑19.
This evidence summary sets out the best available evidence on vitamin D for preventing or treating COVID‑19, or for the susceptibility to COVID‑19 based on vitamin D status. Treating or preventing acute respiratory tract infections more generally was out of scope. The Scientific Advisory Committee on Nutrition (SACN) has published a report on vitamin D and acute respiratory tract infections.