Relevance to NICE guidance programmes
Racecadotril was not considered appropriate for a NICE technology appraisal and is not currently planned into any other NICE work programme.
NICE has not published guidance on managing acute diarrhoea due to gastroenteritis in adults. Diarrhoea and vomiting caused by gastroenteritis: diagnosis, assessment and management in children younger than 5 years (NICE clinical guideline 84) was published in 2009. The Guideline Development Group reviewed 2 randomised placebo-controlled trials that looked at the effectiveness of racecadotril for treating diarrhoea in children. The Guideline Development Group concluded that, at that time, there was evidence that racecadotril had an antidiarrhoeal effect but further research was needed to examine the possible clinical and health economic benefits that might be associated with its use in the UK.