Appendix: Search strategy and evidence selection

Appendix: Search strategy and evidence selection

Search strategy

General background, guidelines and technology assessments:

  • Broad internet search: Google e.g.: allintitle: bronchiectasis Colistimethate OR Colomycin OR colistin OR coly OR promixin

  • Trip Database

MEDLINE (via Ovid)

Database: Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) <1946 to Present>

Search Strategy:

1. exp Bronchiectasis/ (7478)

2. "bronchiectasi*".af. (9482)

3. 1 or 2 (10301)

4. Colistin/ (2313)

5. (Colistimethate or Colomycin or colistin or coly* or promixin).af. (4179)

6. 4 or 5 (4179)

7. 3 and 6 (18)

Embase (via Ovid)

Database: Embase <1988 to 2013 September 17>

Search Strategy:

1. exp bronchiectasis/ (8343)

2. "bronchiectasi*".af. (9447)

3. 1 or 2 (9849)

4. colistimethate/ (489)

5. (Colistimethate or Colomycin or colistin or coly* or promixin).af. (7410)

6. 4 or 5 (7410)

7. 3 and 6 (141)

8. limit 7 to english language (127)

Cochrane Central Register of Controlled Trials (CENTRAL)

1. MeSH descriptor: [Bronchiectasis] explode all trees

2. bronchiectasis:ti,ab,kw (Word variations have been searched)

3. #1 or #2

4. (Colistimethate or Colomycin or colistin or coly* or promixin):ti,ab,kw (Word variations have been searched)

5. #3 and #4

CRD HTA, DARE and EED database

(Colistimethate or Colomycin or colistin or coly or promixin) and bronchiectasis

Manufacturers' websites

Forest Labs

Evidence selection

No published randomised controlled trials of colistimethate sodium for non-cystic fibrosis bronchiectasis were identified. After excluding conference abstracts and poster presentations, only 4 observational case series were identified that reported use of nebulised or inhaled colistimethate sodium in this population, and all were included in the evidence summary.