• The technology described in this briefing is the Butterfly iQ+. It is used for external diagnostic ultrasound imaging in adults and children.

  • The innovative aspects are that it is the first handheld device that can be used for multiple applications, with a single probe emulating different probe types. It is powered by a single silicon chip, 'ultrasound on a chip', and connected to a smartphone. It could be used in settings where there is no access to alternative ultrasound equipment.

  • The intended place in therapy would be as an alternative to point‑of‑care ultrasound devices for people who need diagnostic ultrasound imaging.

  • The main points from the evidence summarised in this briefing are from 5 observational studies including 174 people. They show that the Butterfly iQ+ can be effective as a diagnostic ultrasound tool across a variety of indications.

  • Key uncertainties around the technology are that experts expressed concerns about image quality and size on a smartphone screen. Key uncertainties around the evidence are that there were only 2 comparative studies, and these did not report patient outcomes. Also, only 1 study was done in the UK.

  • The cost of Butterfly iQ+ is £1,699 per unit, plus £360 per year as a membership fee (excluding VAT). Standard care costs between £6,000 and £19,500 for point‑of‑care ultrasound devices and between £30,000 and £100,000 for traditional cart‑based ultrasound devices.