Do Not Do Recommendation

 
Current evidence on the safety and efficacy of EPITHELIUM-ON (transepithelial) corneal collagen cross-linkage (CXL), and the combination (CXL-plus) procedures for keratoconus and keratectasia is inadequate in quantity and quality. Therefore, these procedures should only be used with special arrangements for clinical governance, consent and audit or research. Note that current evidence on the safety and efficacy of EPITHELIUM-OFF CXL for keratoconus and keratectasia is adequate in quality and quantity.

Do Not Do Recommendation Details

Recommendation:
Current evidence on the safety and efficacy of EPITHELIUM-ON (transepithelial) corneal collagen cross-linkage (CXL), and the combination (CXL-plus) procedures for keratoconus and keratectasia is inadequate in quantity and quality. Therefore, these procedures should only be used with special arrangements for clinical governance, consent and audit or research. Note that current evidence on the safety and efficacy of EPITHELIUM-OFF CXL for keratoconus and keratectasia is adequate in quality and quantity.
Interventions:
Corneal collagen cross-linkage for kerataconus

Source guidance details

Guidance:
Photochemical corneal collagen cross-linkage using riboflavin and ultraviolet A for keratoconus and keratectasia (IPG466)
Published date:
September 2013
Paragraph number:
1.2
Page number:
2

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There are no other recommendations for this guidance.