Do Not Do Recommendation

 

Do not use antidepressants routinely to treat persistent subthreshold depressive symptoms or mild depression because the risk–benefit ratio is poor, but consider them for people with:

  • a past history of moderate or severe depression or
  • initial presentation of subthreshold depressive symptoms that have been present for a long period (typically at least 2 years) or
  • subthreshold depressive symptoms or mild depression that persist(s) after other interventions.

Do Not Do Recommendation Details

Recommendation:

Do not use antidepressants routinely to treat persistent subthreshold depressive symptoms or mild depression because the risk–benefit ratio is poor, but consider them for people with:

  • a past history of moderate or severe depression or
  • initial presentation of subthreshold depressive symptoms that have been present for a long period (typically at least 2 years) or
  • subthreshold depressive symptoms or mild depression that persist(s) after other interventions.
Interventions:
Use of Antidepressants

Source guidance details

Guidance:
Depression in adults: recognition and management (CG90)
Published date:
June 2016
Paragraph number:
14.4.1
Page number:
20

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