Technology appraisal committee meeting (committee B)

03 December 2025

via Zoom

Draft Agenda

 The meeting will take place via Zoom, a secure web conferencing tool.

The meeting will run from 8:45am to 4:30pm, although this may be subject to change.  Joining links and times for each topic and further instructions will be sent 1-2 days before the meeting.

Please note that this agenda is a draft and is suject to change before the meeting.

  1. Welcome and introduction to format of meeting – Part 1 only (open session)
  2. Apologies – Part 1 only (open session)
  3. Any other business – Part 1 only (open session)
    3.1. Minutes from the last committee meeting held on 5 November 2025 – Part 1 only (open session)
  4. Appraisal of talazoparib with enzalutamide for untreated hormone-relapsed metastatic prostate cancer [ID4004]
    • 4.1. Intoduction by the Chair, Dr Charles Crawley – Part 1 only (open session)
    • 4.2. Declaration of interests – Part 1 only (open session)
    • 4.3. Presentation by the Chair, Dr Charles Crawley – Part 1 AND part 2 (open and closed session)
    • 4.4. Agreement on the content of the Draft Guidance (DG) or Final Draft Guidance (FDG) – Part 2 only (closed session)
  5. Appraisal of daratumumab with bortezomib, lenalidomide and dexamethasone for untreated multiple myeloma when a stem cell transplant is unsuitable [ID3843]
    • 5.1. Intoduction by the Chair Dr Charles Crawley – Part 1 only (open session)
    • 5.2. Declaration of interests – Part 1 only (open session)
    • 5.3. Presentation by the lead team; Lisa Attrill, Nigel Westwood and Mariana Bacelar  – Part 1 AND part 2 (open and closed session)
    • 5.4. Agreement on the content of the Draft Guidance (DG) or Final Draft Guidance (FDG) – Part 2 only (closed session)
  6. Appraisal of daratumumab with bortezomib, lenalidomide and dexamethasone for untreated multiple myeloma when an autologous stem cell transplant is suitable [ID6249] 
    • 6.1. Intoduction by the Chair Dr Charles Crawley – Part 1 only (open session)
    • 6.2. Declaration of interests – Part 1 only (open session)
    • 6.3. Presentation by the lead team -  Lisa Attrill, Nigel Westwood and Mariana Bacelar  – Part 1 AND part 2 (open and closed session)
    • 6.4. Agreement on the content of the Draft Guidance (DG) or Final Draft Guidance (FDG) – Part 2 only (closed session)

To print an agenda, please right click and select 'Print' from the menu.

Important information on how to register

  • Click on the register link below and complete the registration form, selecting the topics you would like to observe.
  • You will receive an automated email response when you submit the registration form. If you do not receive this automated response your registration request has not been received, and you will need to complete and submit the registration form again.
  • Registration will close on Wednesday 26 November 2025.
  • When registration closes you will receive a confirmation email whether you have been allocated a place or not. You must let us know if you intend to keep this place at least 5 working days before the meeting.
  • We will add your registration details to the virtual web conferencing tool (Zoom) and joining instructions will be sent about 1-2 days before the meeting.
  • We will not be able to accept any late requests or name changes after we have registered attendees for the virtual Zoom meeting.

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  • Should you have any queries regarding observing this meeting, please contact the Meetings in Public Coordinator.
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  • Further information about conducting research is also available in our common questions and answers about meetings in public document

REGISTRATION IS NOW CLOSED

As you have registered directly on Zoom, please make sure you note the meeting date and time in your diary. You will receive confirmation with your joining link and further information once registration has closed.

  • Date and time of next meeting

    The next meeting will take place on day Wednesday 14 January 2026 at 9.00am, via Zoom.

    Please note all timings are approximate.