About this information

NICE clinical guidelines advise the NHS on caring for people with specific conditions or diseases and the treatments they should receive. The information applies to people using the NHS in England and Wales.

In April 2018, we updated the advice in the guideline with warnings about sodium valproate. Sodium valproate must not be used in pregnancy, and only used in girls and women when there is no alternative and a pregnancy prevention plan is in place. This is because of the risk of malformations and developmental abnormalities in the baby.

This information explains the advice about treating people with depression that is set out in NICE clinical guidelineĀ 90.

This is an update of advice on depression that NICE produced in 2004.

Does this information apply to me?

Yes, if you are:

  • an adult (aged 18 and over) with depression

  • a family member or carer of an adult with depression.

The advice in the NICE guideline does not specifically look at the care and treatment of people with both depression and a long-term physical health problem (NICE has produced separate advice about this).

  • Information Standard