3 Information about cefiderocol

3.1 Cefiderocol is a siderophore cephalosporin. It inhibits gram-negative bacterial cell wall synthesis by binding to penicillin-binding proteins. Cefiderocol is administered as an intravenous infusion over 2 hours, and given every 8 hours. Dosage adjustment is needed for people with renal impairment.

Marketing authorisation indication

3.2 Cefiderocol (Fetcroja, Shionogi) is indicated 'for the treatment of infections due to aerobic gram-negative organisms in adults with limited treatment options'.

Dosage in the marketing authorisation

3.3 The dosage schedule is available in cefiderocol's summary of product characteristics.