The National Institute for Health and Clinical Excellence (NICE) issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on Tissue-cultured limbal stem cell allograft transplantation for regrowth of corneal epithelium.

The guidance was considered for reassessment in October 2010 and it was concluded that NICE will not be updating this guidance at this stage. However, if you believe there is new evidence which should warrant a review of our guidance, please contact us via the email address below.

Description

Limbal Corneal tissue is obtained either from eyes donated to the hospital eye bank or living relatives. Small amounts of tissue are digested to break apart cells and these are grown and amplified in culture. Sheets of cells are transplanted to affected eyes.

Coding recommendations

C46.7 Transplant of corneal limbal cells

Note: Use a subsidiary code to identify type of graft (Y27)

Y27.2 Allograft to organ NOC

Your responsibility

This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expected to take this guidance fully into account. However, the guidance does not override the individual responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or guardian or carer.

Commissioners and/or providers have a responsibility to implement the guidance, in their local context, in light of their duties to have due regard to the need to eliminate unlawful discrimination, advance equality of opportunity, and foster good relations. Nothing in this guidance should be interpreted in a way that would be inconsistent with compliance with those duties.