1.1 Evidence on safety and efficacy outcomes of MR image-guided percutaneous laser ablation of uterine fibroids is insufficient to support its use without special arrangements for consent and for audit or research. Clinicians wishing to undertake MR image-guided percutaneous laser ablation should inform the clinical governance leads in their Trusts. They should ensure that women offered the procedure understand the uncertainty about its safety and efficacy and should provide them with clear written information. Use of the Institute's information for the public is recommended. Clinicians should ensure that appropriate arrangements are in place for audit or research. Publication of safety and efficacy outcomes will be useful in reducing the current uncertainty. NICE is not undertaking further investigation at present.