The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on endovascular closure of atrial septal defect.


An atrial septal defect is the persistence of a hole (the foramen ovale) in the wall (septum) between the right atrium and left atrium of the heart.  The foramen ovale usually closes spontaneously after birth; an atrial septal defect is present when this closure does not occur. In the most common type, an ostium secundum atrial septal defect, the septum between the atria fails to form properly during foetal development, resulting in a permanent hole. An atrial septal defect allows blood to flow from the left atrium to the right atrium, so increasing the flow of blood to the lungs. This is known as a shunt. Patients with atrial septal defects are usually asymptomatic through infancy and childhood. Symptoms such as exertional dyspnoea, fatigue, palpitations and syncope can occur and increasing age carries an increasing risk of stroke. Some patients may develop congestive heart failure.

Endovascular closure of an atrial septal defect involves making a small incision in the groin to introduce a guidewire and delivery sheath into the femoral vein. An occluder device is then introduced through the delivery sheath on a semi-rigid cable and expanded within the atrial septal defect to close it. Echocardiography and fluoroscopic guidance are used to determine the size and position of the defect and to place the occluder device. A balloon may be used to measure the diameter of the defect. People can usually go home the next day. Small residual shunts after the procedure often resolve as endothelial tissue grows over and around the device. The claimed advantages compared with open surgery are shorter hospital stay, earlier return to normal activities and fewer complications.

Coding and clinical classification codes for this guidance.