Recommendations for research

The guideline committee has made the following recommendations for research.

1 Diagnostic accuracy of endoscopic surveillance

What is the diagnostic accuracy of different endoscopic surveillance techniques including high resolution endoscopy and chromoendoscopy for use in adults?

For a short explanation of why the committee made this recommendation for research, see the rationale section on endoscopic surveillance.

Full details of the evidence and the committee's discussion are in evidence review F: frequency and duration of endoscopic surveillance techniques.

2 Frequency and duration of endoscopic surveillance

What is the usefulness of clinical and molecular biomarkers to inform the optimal frequency and duration of endoscopic surveillance for adults with Barrett's oesophagus?

For a short explanation of why the committee made this recommendation for research, see the rationale section on endoscopic surveillance.

Full details of the evidence and the committee's discussion are in evidence review F: frequency and duration of endoscopic surveillance techniques.

3 Oesophagectomy

What is the effectiveness of endoscopic resection with or without adjuvant chemoradiotherapy and oesophagectomy for adults with T1b oesophageal adenocarcinoma?

For a short explanation of why the committee made this recommendation for research, see the rationale section on managing stage 1 oesophageal adenocarcinoma.

Full details of the evidence and the committee's discussion are in evidence review K: oesophagectomy versus endoscopy treatment.

4 Endoscopic treatments

For adults with Barrett's oesophagus with dysplasia, what is the effectiveness of different endoscopic ablation techniques alone or in combination with endoscopic resection?

For a short explanation of why the committee made this recommendation for research, see the rationale section on managing Barrett's oesophagus with dysplasia.

Full details of the evidence and the committee's discussion are in evidence review H: endoscopic treatment (high-grade dysplasia and stage 1 adenocarcinoma).

For adults with stage 1 oesophageal adenocarcinoma, what is the effectiveness of different endoscopic ablation techniques alone or in combination with endoscopic resection?

For a short explanation of why the committee made this recommendation for research, see the rationale section on managing stage 1 oesophageal adenocarcinoma.

Full details of the evidence and the committee's discussion are in evidence review H: endoscopic treatment (high-grade dysplasia and stage 1 adenocarcinoma)

5 Frequency and duration of endoscopic follow-up

What is the optimal frequency and duration of endoscopic follow-up for patients who have received endoscopic treatment for Barrett's oesophagus with dysplasia?

For a short explanation of why the committee made this recommendation for research, see the rationale section on managing Barrett's oesophagus with dysplasia.

Full details of the evidence and the committee's discussion are in evidence review J: endoscopic and radiological follow-up after treatment.

What is the optimal frequency and duration of endoscopic follow-up for patients who have received endoscopic treatment for stage 1 oesophageal adenocarcinoma?

For a short explanation of why the committee made this recommendation for research, see the rationale section on managing stage 1 oesophageal adenocarcinoma.

Full details of the evidence and the committee's discussion are in evidence review J: endoscopic and radiological follow-up after treatment.

  • National Institute for Health and Care Excellence (NICE)